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REVIEW ARTICLE
Year : 2021  |  Volume : 5  |  Issue : 2  |  Page : 45-48

Emergence, virology, immune response after SARS-CoV-2 infection, and role of immunopathology behind vaccination


Department of Pathology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, India

Correspondence Address:
R Priyadharshini
Department of Pathology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/ijcpc.ijcpc_15_21

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In mid-January 2020, the WHO received information from the International Commission of Health about an outbreak of disease in the capital of Hubei province, Wuhan, in Central China. There was no evidence of human transmission or infection among health-care workers at that stage. Initially, the cases identified visiting the Wuhan live and seafood market prompted a suspicion that might be the source of the pandemic. Stumbling of more than 200 vaccines started with preclinical progress, but only approximately 40 vaccines entered clinical trials where some were not approved for human trials. This review addresses the genome sequence, immunopathology induced by virus, and vaccine.


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